For many women the early weeks of pregnancy includes some bouts of morning sickness, that eventually stop. But for others it’s a never-ending cycle of extreme nausea and vomiting so severe that they consider ending their pregnancy.
A new study has revealed the shocking impact of hyperemesis gravidarum (HG), a severe form of nausea and vomiting in pregnancy, on expecting mums in Australia.
More than half of women dealing with the extreme morning sickness reported they considered terminating their pregnancy. While nine out of 10 said they’d thought about not having any more children.
“Hyperemesis gravidarum is not just morning sickness—it’s a serious condition that can have devastating consequences for women’s mental health, relationships, and decisions about future pregnancies,” explained lead author Associate Professor Grzeskowiak.
The pharmacist and researcher from Flinders University said the findings also identified the mixed effectiveness of current treatment options.
“Our study shows that many women are not getting the support or relief they need, and that’s something we must urgently address,” he said.

The survey of 289 Australian women found:
- 54% considered terminating a pregnancy because of HG symptoms.
- 90% considered not having more children.
- 62% reported ‘often’ or ‘always’ feeling anxious or depressed during pregnancy.
- 37% requested an early induction of labour to end their pregnancy sooner.
And only half of the women surveyed said the commonly-used treatments for HG were effective.
The women reported that ondansetron, doxylamine and corticosteroids were the most effective medications, but they reported significant side effects, including constipation, sedation, and impaired cognition.
Almost one-third of women stopped using another frequently used drug, Metoclopramide, because of adverse effects.
“Women are often prescribed multiple medications in an attempt to manage their symptoms, but the reality is that many of these treatments come with their own burdens,” said Associate Professor Grzeskowiak.
“We need better evidence to guide treatment decisions and ensure women are supported to make informed choices.”
Study co-author, Caitlin Kay-Smith, founder of consumer organisation Hyperemesis Australia, said the findings should shine a light on how HG is treated and managed.
“We need to move away from a one-size-fits-all approach and toward personalised care that recognises the full impact of HG,” she said.
Did you suffer from severe morning sickness? What worked for you? Let us know in the comments below.






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