We already know the significant benefits the nutrient choline has on the developing brain during pregnancy, with offspring showing improvements in cognition, attention and memory.  Now new research published in the Neurobiology Disease Journel, shows additional benefits of choline in Down syndrome.

Findings from the study indicate that a higher consumption of choline by the mother lessens the impairment of children with Down syndrome as well as reducing the risk of Alzheimer’s disease, which is common in people with Down syndrome.

“While older pregnant women are generally tested for a Down syndrome fetus, younger women are not, since their risk is low.  However, development of all fetuses – Down syndrome or now – would benefit from choline supplements during pregnancy” said Barbara Strupp, Cornell professor of nutritional sciences and psychology and senior study author.

Researchers found that the increased choline in the mothers diet improved brain function at a cellular level, by bolstering brain cell formation, particularly in the memory centre of the brain.

“Mounting evidence suggests that many women may not be consuming enough choline during pregnancy to promote optimal brain development and cognitive functioning of their babies – both normal and Down syndrome.  Increasing choline intake during pregnancy is sound nutritional advice for all women and may offer and even more pronounced benefit for Down syndrome offspring,” said Professor Strupp.

Professor Strupp explains that choline is an essential nutrient for everyone, but pregnant women have an even greater demand to support the developing fetus.

Recommended adequate intake for women prior to pregnancy is

  • 425mg for women 19 – 70+ years
  • 440mg during pregnancy 18 – 50 years
  • 550mg during breastfeeding 18 – 50 years

Good sources of choline include lecithin granules, eggs, beef, salmon, chicken, baked beans, kidney beans, lentils, brussel sprouts, broccoli, spinach, cauliflower, wheatgerm, oats and milk.  Good pregnancy supplements should also provide the recommended adequate intake of choline, such as Zycia Natal Nutrients.

  • I had never heard of choline before this article


  • I’d still double-check with my doctor before taking a supplement when pregnant. And while it’s easy to say that if you eat properly, then you should get all the nutrients you need, sometimes life gets in the way of the best of intentions, and you need a bit of extra help.


  • There’s so many recommendations! I opted to take a pregnancy multi vitamin to make sure I was getting everything I needed!


  • if you eat right then you shouldn’t need a substitute for choline


  • I had not heard about this before


  • Good article , thanks for sharing


  • if you have a good varied diet you should be getting all the nutrients necessary, check with your doctor for advice.


  • Interesting. I shall keep that in mind for the next one


  • thanks for sharing was a good read


  • interesting read – thanks for sharing


  • Thank you for sharing, great article :) xx


  • thanks for sharing was a great read


  • Thanks for sharing. I really enjoyed reading it. Great information .This is a really interesting article and well worth the read.


  • I’ve never heard of choline might have to ask my health food store


  • should people in general increase their amount of choline then?

    • For sure. It’s beneficial for everyone to support healthy brain function. Initial studies actually began supporting reduction in memory decline later in life


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