Women who take ibuprofen in the first six months of pregnancy may harm their daughters’ future fertility.

Scientists found the common painkiller can halve the number of egg cells in girls’ ovaries.

This suggests girls exposed to ibuprofen in the womb may struggle to have a family, as their body makes fewer eggs, shares Daily Mail.

A study led by the French National Institute of Health and Medical Research exposed tissue from human ovaries to ibuprofen. The amount was the same as two to seven days of a woman taking the drug in pregnancy.

They found egg cells either died or failed to grow and multiply at the normal rate. Study co-author Dr Severine Mazaud-Guittot said: ‘The development of the follicles in the foetus has not been completed by the end of the first trimester, so if the ibuprofen treatment is short then we can expect the ovarian reserve to recover to some extent.

‘However, we found that two to seven days of exposure to ibuprofen dramatically reduced the germ cell stockpile in human foetal ovaries during the first trimester of pregnancy and the ovaries did not recover fully from this damage.

‘This suggests that prolonged exposure to ibuprofen during foetal life may lead to long-term effects on women’s fertility and raises concern about ibuprofen consumption by women during the first 24 weeks of pregnancy. These findings deserve to be considered in light of the present recommendations about ibuprofen consumption during pregnancy.’

The NHS recommends that women avoid taking ibuprofen in the first 30 weeks of pregnancy, ‘unless the benefits outweigh the potential risk of your unborn baby’.

Professor Hans Evers, editor of the journal Human Reproduction, said: ‘These are important findings that require further investigation. However, at this stage it is not possible to say whether the reduced numbers of follicles in tissue samples from baby girls might translate into reduced fertility 30 years later. At present this is speculation and requires long-term follow-up studies of daughters of women who took ibuprofen while in their first three months of pregnancy.’

Australian researchers have also discovered the risks to your baby if you take antibiotics while pregnant. READ MORE HERE

Share your comments below.

  • Wonder if this could cause a lot of miscarriages too.


  • This is rather interesting, thank you.


  • Wow! I actually can’t remember if I did this or not when I was pregnant now…


  • I always only take Panadol if its really bad and when I was pregnant I pretty much put up with everything because I was always concerned about what entered my body.


  • I’m not someone who takes ibuprofen but this info is good to know and share. I would always check with my Doctor during pregnancy about what I could and could not take.


  • That is not the only way you can be effected by Iboprufen. It actually leeches out of your skin for about 10 – 12 hours (depending on the dosage). Skin to skin transfer can result in reaction especially if you are allergic to it. In somebody who is allergic to it, it can cause breathing problems – even anaphalexia in severe cases. Until it happens a couple of times you may not realise you are allergic to it. Reaction the first time might be loss of balance, and get worse. It can also effect your brain. The more you come into contact with it the more damage it does. I know a boy who is being home schooled because the school is unable to make sure no pupil has taken any either that day or the day before.


  • I never have something else then paracetamol and even that I try to avoid taking, whether I’m pregnant or not.


  • As someone who suffers low blood pressure during pregnancy, I was always told not to take ibuprofen as it can thin your blood too. Not a good combo. Sucks too, its the only thing that helps migraines, it just means I have to take lots of precautions to avoid migraine triggers.


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